Drug Uses
Transderm Scop is used to relieve nausea, vomiting, and dizziness associated with motion sickness. Transderm Scop is an anticholinergic medicine. Anticholinergics have many effects in the body. For example, they decrease the secretion of fluids, slow the stomach and intestine, and dilate the pupils.
How Taken
Transderm Scop comes as a patch to be placed on the skin behind your ear. Apply one patch to a clean, dry, hairless area behind the ear. The patch should be applied at least 4 hours before its effects will be needed. Each patch is good for 3 days. At the end of 3 days or when the Transderm Scop patch is no longer needed, remove the patch and throw it away. Wrap the patch in tissue or paper to avoid exposing anyone else to the remaining medication. Wash your hands and the area behind your ear thoroughly to remove any traces of Transderm Scop from the area. If a new patch needs to be applied, place a fresh patch on the hairless area behind your other ear.
Warnings/Precautions
Before using this medication, tell your doctor if you have kidney disease, liver disease, an enlarged prostate, difficulty urinating, bladder problems, or glaucoma.
Transderm Scop is in the FDA pregnancy category C. This means that it is not known whether Transderm Scop will harm an unborn baby. Do not use Transderm Scop without first talking to your doctor if you are pregnant.
It is not known whether Transderm Scop passes into breast milk. Do not use Transderm Scop without first talking to your doctor if you are breast-feeding a baby.
Transderm Scop is not recommended for children use. Children are much more sensitive to the side effects of scopolamine.
Missed Dose
Remove the old patch as soon as you remember and apply a new patch to the same area behind the other ear. If it is almost time for the next dose, skip the missed dose altogether. Never take a double dose of Transderm Scop.
Possible Side Effects
Stop using Transderm Scop and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).
Other, less serious side effects may be more likely to occur. Continue to use Transderm Scop and talk to your doctor if you experience drowsiness; dry mouth, nose, or throat; restlessness, excitation, nervousness, or insomnia; blurred vision; dizziness; decreased appetite, nausea, or vomiting; difficulty urinating; or an irregular or fast heartbeat.
Nausea, vomiting, dizziness, headache, and poor coordination have been reported when treatment lasting more than 3 days is discontinued. If you use Transderm Scop for more than 3 days, be aware that these side effects may occur when you stop.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Storage
Should be stored at controlled room temperature between 20°C - 25°C (68°F - 77°F).
Overdose
Seek emergency medical attention. Symptoms of a Transderm Scop overdose include drowsiness, dizziness, agitation, excitability, seizures or convulsions, hallucinations, and death.
More Information
Use caution when driving, operating machinery, or performing other hazardous activities. Transderm Scop may cause dizziness, drowsiness, or blurred vision. If you experience dizziness, drowsiness, or blurred vision, avoid these activities.
Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are using Transderm Scop.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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What is motion sickness?
Motion sickness is a very common disturbance of the inner ear that is caused by repeated motion such as from the swell of the sea, the movement of a car, the motion of a plane in turbulent air, etc. In the inner ear (which is also called the labyrinth), motion sickness affects the sense of balance and equilibrium and, hence, the sense of spatial orientation.
What causes motion sickness?
Motion is sensed by the brain through three different pathways of the nervous system that send signals coming from the inner ear (sensing motion, acceleration, and gravity), the eyes (vision), and the deeper tissues of the body surface (proprioceptors). When the body is moved intentionally, for example, when we walk, the input from all three pathways is coordinated by our brain. When there is unintentional movement of the body, as occurs during motion when driving in a car, the brain is not coordinating the input, and there is thought to be discoordination or conflict among the input from the three pathways. It is hypothesized that the conflict among the inputs is responsible for motion sickness.
For example, when we are sitting watching a picture that depicts a moving scene, our vision pathway is telling our brain that there is movement, but our inner ear is telling our brains that there is no movement. Thus, there is conflict in the brain, and some people will develop motion sickness in such a situation (even though there is no motion).
The cause of motion sickness is complex, however, and the role of conflicting input is only a hypothesis, or a proposed explanation, for its development. Without the motion–sensing organs of the inner ear, motion sickness does not occur, suggesting that the inner ear is critical for the development of motion sickness. Visual input seems to be of lesser importance, since blind people can develop motion sickness. Motion sickness is more likely to occur with complex types of movement, especially movement that is slow or involves two different directions (for example, vertical and horizontal) at the same time.
The conflicting input within the brain appears to involve levels of the neurotransmitters (substances that mediate transmission of signals within the brain and nervous system) histamine, acetylcholine, and norepinephrine. Many of the drugs that are used to treat motion sickness act by influencing or normalizing the levels of these compounds within the brain.
What are the symptoms of motion sickness?
The symptoms of motion sickness include nausea, vomiting, and dizziness (vertigo). Other common signs are sweating and a general feeling of discomfort and not feeling well (malaise).
Is there a difference between motion sickness and sea sickness?
There is no difference between motion sickness and sea sickness. Some people experience nausea and even vomiting when riding in an airplane, automobile, or amusement park ride. This condition is generally called motion sickness. Many people experience motion sickness when riding on a boat or ship. This is commonly referred to as sea sickness (mal de mer), even though it is the same disorder. They are one and the same phenomenon and will subsequently be referred to as motion sickness.
How does our sense of balance work?
Motion sickness relates to our sense of balance and equilibrium. Researchers in space and aeronautical medicine call this sense spatial orientation, because it tells the brain where the body is "in space:" what direction it is pointing, what direction it is moving, and if it is turning or standing still.
Our sense of balance is regulated by a complex interaction of the following parts of the nervous system:
1. The inner ears (also called the labyrinth) monitor the directions of motion, such as turning or forward–backward, side–to–side, and up–and– down motions.
2. The eyes observe where the body is in space (for example, upside down, right side up, etc.) and also the directions of motion.
3. Skin pressure receptors such as those located in the feet and seat sense what part of the body is down and touching the ground.
4. Muscle and joint sensory receptors report what parts of the body are moving.
5. The central nervous system (the brain and spinal cord) processes all the bits of information from the four other systems to make some coordinated sense out of it all.
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