Drug Uses

Elidel is a prescription medicine you put on your skin (topical) to treat atopic dermatitis, also known as eczema. Elidel is for use on the skin only. Elidel is for adults and children age 2 years and older. You can use Elidel for short or intermittent long periods of treatment. Intermittent means starting and stopping repeatedly, as directed by your doctor. You can use it on all affected areas of your skin, including your face and neck.

How Taken

Apply a thin layer of Elidel cream 1% to the affected skin twice daily and rub in gently and completely. Elidel may be used on all skin surfaces, including the head, neck. Elidel should be used twice daily for as long as signs and symptoms persist. Treatment should be discontinued if resolution of disease occurs. If symptoms persist beyond 6 weeks, the patient should be re-evaluated. The safety of Elidel Cream under occlusion, which may promote systemic exposure, has not been evaluated. Elidel cream should not be used with occlusive dressings.

Warnings/Precautions

Do not use Elidel without first talking to your doctor if you have the congenital skin disorder Netherton's syndrome. Before using Elidel, tell your doctor if you: have a skin infection; have a disease of the immune system; or are using any other type of skin product (e.g., cream, ointment, lotion, etc.). You may not be able to use Elidel, or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above. Elidel is in the FDA pregnancy category C. This means that it is not known whether Elidel will harm an unborn baby. Do not use this medication without first talking to your doctor if you are pregnant or are planning to become pregnant during treatment. It is not known whether Elidel passes into breast milk. Do not use this medication without first talking to your doctor if you are breast-feeding a baby. Elidel is not approved for use by children younger than 2 years of age.

Missed Dose

Use the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed, and use only the next regularly scheduled dose.

Possible Side Effects

The most common side effect at the site of application is burning or a feeling of warmth. The burning feeling is usually mild or moderate, occurring in the first 5 days of treatment, and the burning usually clears up in a few days. See your doctor if an application site reaction is severe or persists for more than 1 week. Other common side effects include headache, and with long-term intermittent use, common cold/stuffy nose, influenza, sore throat, fever, viral infection, and cough. Some people may get herpes skin infections (like cold sores, chicken pox, or shingles), warts, or swollen lymph nodes (glands).

Storage

Store at 25°C (77°F); excursions permitted to 15°C-30°C (59°F-86°F). Do not freeze.

Overdose

There has been no experience of overdose with Elidel cream 1%. If oral ingestion occurs, medical advice should be sought.

More Information

Avoid sunlight and sun lamps, tanning beds, and treatments with UVA or UVB light. If you need to be outdoors after applying Elidel, wear loose clothing that protects the treated area from the sun. Also, ask your doctor what other type of protection from the sun may be needed. Unless otherwise instructed by your doctor, do not apply any other skin products on the areas treated with Elidel.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Smokers' Skin Is More Wrinkled, Even In Areas Shielded From Sunlight
Science Daily — In classic movies, cigarette smoking was used as shorthand to convey sultriness and beauty. In the real world, the connection between smoking and one's appearance -- as many studies have shown -- has more to do with premature signs of aging and less to do with glamour and refinement.
A new study from the University of Michigan Health System adds another dimension to the link between cigarette smoking and skin damage. The study suggests that smoking may be associated with a higher degree of aging on areas of skin, such as that of the inside of the upper arm, that are not normally exposed to sunlight.
"We examined non-facial skin that was protected from the sun, and found that the total number of packs of cigarettes smoked per day and the total years a person has smoked were linked with the amount of skin damage a person experienced," says Yolanda R. Helfrich, M.D., lead author and assistant professor of dermatology at the U-M Medical School.
The researchers developed a photonumeric scale that can be easily reproduced by other medical institutions to measure the degree of aging on patients' skin. The nine-point scale used information from photographs of the inside-upper-arm skin of the 77 participants.
Two medical residents and a medical student were asked to look at the photographs and assign a grade in which zero represented no fine wrinkling and eight represented severe fine wrinkling. The same three people reviewed photos of the participants one year later, and the scores were used to determine the level of increase in the skin damage.
Researchers also collected data about the participants from interviews, such as their age, ethnicity, history of cigarette smoking, use of non-steroidal anti-inflammatory drugs, use of dietary or herbal supplements, sun exposure, sunscreen use, tanning bed use and, for women, how many children they had given birth to, hormone therapy use and oral contraceptive use.
Among the people in the study who were current or former smokers, they had smoked an average of about 24 years. In all, among participants who were 45 years or older, the degree of skin aging was found to be significantly higher in smokers than nonsmokers.
In the 45-65 age group, smokers had an average score on the photonumeric scale of more than two, while nonsmokers had an average score of less than one. In the 65 and older age group, smokers had an average score of about six, while nonsmokers had an average score of approximately four.
In addition to Helfrich, authors were Abena Ofori, M.D.; Ted A. Hamilton, M.S.; Jennifer Lambert, M.S.; Anya King, M.P.H.; John J. Voorhees, M.D.; and senior author Sewon Kang, M.D., all of the U-M Department of Dermatology; and Le Yu, M.D., now with Cedars Sinai Medical Center in Los Angeles.

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